Identify the incorrect statement.

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(C) The correct answer is $C$. $1$. Phenylketonuria is an autosomal recessive disorder caused by a mutation in the gene for the enzyme phenylalanine h

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Sickle cell anemia is an $X$-linked recessive gene disorder.

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(C) The correct answer is $C$. $1$. Phenylketonuria is an autosomal recessive disorder caused by a mutation in the gene for the enzyme phenylalanine hydroxylase. $2$. Down syndrome is a chromosomal disorder caused by the presence of an extra copy of chromosome $21$ (trisomy $21$),which is a type of aneuploidy. $3$. Sickle cell anemia is an autosomal recessive disorder,not an $X$-linked disorder. It is caused by a mutation in the hemoglobin beta gene on chromosome $11$. $4$. Hemophilia is a well-known $X$-linked recessive disorder where blood fails to clot properly.

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