What was the transforming principle identifie | vedclass

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(B) Oswald Avery,Colin MacLeod,and Maclyn McCarty worked to determine the biochemical nature of the 'transforming principle' in Griffith's experiment.

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$DNA$

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(B) Oswald Avery,Colin MacLeod,and Maclyn McCarty worked to determine the biochemical nature of the 'transforming principle' in Griffith's experiment.They purified biochemicals (proteins,$DNA$,$RNA$,etc.) from the heat-killed $S$ strain of Streptococcus pneumoniae.They discovered that $DNA$ alone from the heat-killed $S$ strain caused the transformation of non-virulent $R$ strain bacteria into virulent $S$ strain bacteria.They also observed that protein-digesting enzymes (proteases) and $RNA$-digesting enzymes (RNases) did not affect transformation,whereas $DNA$-digesting enzymes (DNases) inhibited the process.Thus,they concluded that the genetic material is $DNA$.

What was the transforming principle identified by Avery,MacLeod,and McCarty in Pneumococcus?

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