The reaction of o-methoxychlorobenzene with s | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(B) The reaction of $o-$methoxychlorobenzene with $NaNH_2$ proceeds via the benzyne mechanism. In $o-$methoxychlorobenzene,the methoxy group $(-OCH_3)

Vedclass · Accepted Answer

$m-$methoxyaniline

Vedclass · Answer

(B) The reaction of $o-$methoxychlorobenzene with $NaNH_2$ proceeds via the benzyne mechanism. In $o-$methoxychlorobenzene,the methoxy group $(-OCH_3)$ is an electron-donating group by resonance. When $NaNH_2$ is added,it abstracts the ortho-hydrogen to form a benzyne intermediate. The nucleophilic attack by the amide ion $(NH_2^-)$ on the benzyne intermediate is directed by the inductive effect of the methoxy group. The methoxy group exerts an electron-withdrawing inductive effect ($-I$ effect) at the ortho position,which makes the meta-carbon more electrophilic. Consequently,the nucleophile attacks the meta-position,leading to the formation of $m-$methoxyaniline as the major product.

The reaction of $o-$methoxychlorobenzene with sodamide $(NaNH_2)$ followed by treatment with ammonia yields ........

Similar Questions

Replacement of $Cl$ of chlorobenzene to give phenol requires drastic conditions,but chlorine of $2,4-$dinitrochlorobenzene is readily replaced because:

Consider the following reaction:

The above reaction requires which of the following reaction conditions?

In the Wurtz-Fittig reaction,a compound $X$ reacts with an alkyl halide. What is $X$?

Nitration of phenyl benzoate yields the product

Vedclass Test Series

Exam Paper Generator

Online Exam Module