Which disorder is caused when the synthesis of the $\beta$-globin chain of hemoglobin is affected due to a single gene $HBB$,leading to a quantitative change in the hemoglobin structure?

  • A
    Hemophilia
  • B
    Sickle cell anemia
  • C
    $\beta$-Thalassemia
  • D
    Both $b$ and $c$

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