I. pO_2 is the major factor which affects the | vedclass

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(A) Statement $I$ is correct: The binding of $CO_2$ with haemoglobin is primarily affected by $pO_2$ (Haldane effect).Statement $II$ is incorrect: In

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$I, III$ and $IV$

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(A) Statement $I$ is correct: The binding of $CO_2$ with haemoglobin is primarily affected by $pO_2$ (Haldane effect).Statement $II$ is incorrect: In tissues,$pCO_2$ is high $(45 \; mm \; Hg)$ and $pO_2$ is low $(40 \; mm \; Hg)$ to facilitate gas exchange.Statement $III$ is correct: $RBCs$ contain high concentrations of the enzyme carbonic anhydrase,which facilitates the hydration of $CO_2$.Statement $IV$ is correct: Every $100 \; mL$ of deoxygenated blood delivers approximately $4 \; mL$ of $CO_2$ to the alveoli for elimination.Therefore,statements $I, III,$ and $IV$ are correct.

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