$GAATTC$ is the recognition site for the restriction endonuclease:

Which of the following is a suitable vector for gene cloning in higher organisms?

Which enzyme is used to join the ends of two strands of nucleic acid?

Which microorganism is useful for $PCR$?

Which of the following enzymes hydrolyzes the internal phosphodiester bonds in a polynucleotide chain?

Given below are two statements.
Statement $I$: Restriction enzyme $BamHI$ has its recognition site in $tet^R$ region of $pBR322$.
Statement $II$: $E. coli$ having $pBR322$ with a desired $DNA$ if inserted at $BamHI$ site can grow in medium containing tetracycline.
In the light of the above statements, choose the correct answer from the options given below.