In which of the following conditions are the respiratory centers stimulated?

  • A
    Increase in $O_2$ concentration in the artery
  • B
    Increase in $CO_2$ concentration in the artery
  • C
    Increase in $O_2$ concentration in the vein
  • D
    Increase in $CO_2$ concentration in the vein

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Respiratory centre of the brain is stimulated by

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