Which of the following genotypes results in hemophilia in females and males respectively?
$\quad\quad$ Female $\quad\quad$ Male

What does the given symbol represent in a pedigree chart?

$A$ man whose father was colorblind marries a woman who has a colorblind mother and a normal father. What is the percentage probability of their male children being colorblind (in $\%$)?

If a normal woman marries a colourblind man,what will be the phenotype of their children?

Pick out the correct statements.
$(1)$ Haemophilia is a sex-linked recessive disease.
$(2)$ Down's syndrome is due to aneuploidy.
$(3)$ Phenylketonuria is an autosomal recessive gene disorder.
$(4)$ Sickle cell anaemia is an $X$-linked recessive gene disorder.

Which disease is caused by a gene defect located on chromosome $16$,leading to a deficiency that affects the transport of respiratory gases?