D-(+)-text{Glyceraldehyde} xrightarrow[(ii) H | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(B) The reaction of $D-(+)-	ext{Glyceraldehyde}$ with $HCN$ followed by hydrolysis and oxidation with $HNO_3$ is a Kiliani-Fischer synthesis sequence

Vedclass · Accepted Answer

One optically active and one meso product

Vedclass · Answer

(B) The reaction of $D-(+)-	ext{Glyceraldehyde}$ with $HCN$ followed by hydrolysis and oxidation with $HNO_3$ is a Kiliani-Fischer synthesis sequence.$1$. The addition of $HCN$ to the aldehyde group of $D-(+)-	ext{Glyceraldehyde}$ creates a new chiral center,resulting in two diastereomeric cyanohydrins.$2$. Hydrolysis of these cyanohydrins converts the $-CN$ group into a $-COOH$ group,forming two diastereomeric aldonic acids.$3$. Oxidation with $HNO_3$ further oxidizes the terminal $-CH_2OH$ group to a $-COOH$ group,resulting in two dicarboxylic acids (aldaric acids).$4$. One of the resulting products is $meso-	ext{tartaric acid}$ (or a derivative),which is optically inactive due to an internal plane of symmetry.$5$. The other product is an optically active isomer (e.g.,$L-(+)-	ext{tartaric acid}$ derivative).Thus,the final products are one optically inactive $(meso)$ product and one optically active product.

$D-(+)-\text{Glyceraldehyde} \xrightarrow[(ii) H_2O/H^{+}]{(i) HCN, (iii) HNO_3}$
The products formed in the above reaction are

Similar Questions

Reducing saccharides among the following are:

Sucrose Ribose Maltose Lactose Cellulose

$1$ $2$ $3$ $4$ $5$

Synthesis of each molecule of glucose in photosynthesis involves:

In addition to the aldehyde group,glucose contains . . . . . . .

Consider the following molecules:
Glucose $(K)$,Mannose $(L)$,Galactose $(M)$,$\alpha-Glucose$ $(N)$,$\beta-Glucose$ $(O)$
The correct set of epimer and anomer is respectively:
Epimer - Anomer

What is the number of chiral carbon atoms in threose?

Vedclass Test Series

Exam Paper Generator

Online Exam Module

$D-(+)-\text{Glyceraldehyde} \xrightarrow[(ii) H_2O/H^{+}]{(i) HCN, (iii) HNO_3}$The products formed in the above reaction are