Where are RBCs destroyed? | vedclass

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Question

(A) The $RBCs$ (Red Blood Cells) have a lifespan of approximately $120$ days. After this period,they become fragile and are destroyed primarily in the

Vedclass · Accepted Answer

Kupffer cells

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(A) The $RBCs$ (Red Blood Cells) have a lifespan of approximately $120$ days. After this period,they become fragile and are destroyed primarily in the spleen,which is often called the 'graveyard of $RBCs$'. Within the spleen and liver,specialized macrophages known as Kupffer cells (in the liver) and splenic macrophages engulf and break down the aged $RBCs$ through phagocytosis. Among the given options,Kupffer cells are the phagocytic cells involved in the breakdown of cellular debris,including old $RBCs$.

Where are $RBCs$ destroyed?

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