The most well-known blood grouping system is the $ABO$ system. It is named $ABO$ and not $ABC$ because the $\text{O}$ in it refers to having:

  • A
    No antigens $A$ and $B$ on $RBCs$
  • B
    Other antigens than $A$ and $B$ on $RBCs$
  • C
    Overdominance of $A$ and $B$ type genes
  • D
    Only one antibody - anti-$A$ or anti-$B$ on $RBCs$

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