Which of the following conditions is harmful | vedclass

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(B) Sickle cell anemia is a genetic disorder caused by a mutation in the hemoglobin gene. Individuals who are heterozygous for the sickle cell trait $

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Sickle cell anemia

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(B) Sickle cell anemia is a genetic disorder caused by a mutation in the hemoglobin gene. Individuals who are heterozygous for the sickle cell trait $(Hb^A Hb^S)$ possess a survival advantage in regions where malaria is endemic. The presence of sickle-shaped red blood cells inhibits the growth and reproduction of the malaria parasite $(Plasmodium)$,thereby providing natural resistance against malaria. Thus,while the homozygous condition $(Hb^S Hb^S)$ is harmful,the heterozygous state offers a protective benefit against a mosquito-borne disease.

Which of the following conditions is harmful in itself but also provides protection against a mosquito-borne infectious disease?

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