$I.$ Copy number is defined as the number of copies of a plasmid present in a cell.
$II.$ It varies from $15-100$ copies per cell. Choose the correct option regarding the above statements.

What is the fate of a piece of $DNA$ carrying only the gene of interest which is transferred into an alien organism?
$A$. The piece of $DNA$ would be able to multiply itself independently in the progeny cells of the organism.
$B$. It may get integrated into the genome of the recipient.
$C$. It may multiply and be inherited along with the host $DNA$.
$D$. The alien piece of $DNA$ is not an integral part of the chromosome.
$E$. It shows the ability to replicate.
Choose the correct answer from the options given below:

How is the copy number of the plasmid vector related to the yield of recombinant protein?

What is the full form of $EFB$?

The technique to alter the chemistry of genetic materials, $DNA$ and $RNA$, to introduce these into host organisms and change the phenotype of the host is:

Credit for the construction of the first recombinant $DNA$ is given to: