A chromatography column,packed with silica ge | vedclass

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(B) In silica gel column chromatography,the stationary phase is polar (silica gel,$SiO_2$).Compounds are separated based on their polarity; the least

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$(C), (A)$ and $(B)$

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(B) In silica gel column chromatography,the stationary phase is polar (silica gel,$SiO_2$).Compounds are separated based on their polarity; the least polar compound elutes first,and the most polar compound elutes last.The polarity of the given compounds is determined by their dipole moments and hydrogen bonding capability:$1.$ Acetophenone $(Ph-CO-CH_3)$: Dipole moment $\approx 3.05 \ D$.$2.$ Benzanilide $(Ph-NH-CO-Ph)$: Dipole moment $\approx 2.71 \ D$ (has hydrogen bonding).$3.$ Aniline $(Ph-NH_2)$: Dipole moment $\approx 1.59 \ D$ (has strong hydrogen bonding with silica gel).However,considering the interaction with the polar stationary phase,the elution order depends on the strength of adsorption.Aniline,being a primary amine,interacts strongly with the acidic silanol groups of silica gel.Acetophenone is the least polar among the three.Thus,the elution order is $(C)$ (Acetophenone) followed by $(A)$ (Benzanilide) and finally $(B)$ (Aniline).

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