According to the accepted concept of hormone action,if receptor molecules are removed from target organs,what will be the effect?

• A
  The target organ will continue to respond to the hormone without any difference.
• B
  The target organ will continue to respond to the hormone but will require higher concentration.
• C
  The target organ will not respond to the hormone.
• D
  The target organ will continue to respond to the hormone but in the opposite way.