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(B) The body's immune system is capable of differentiating between 'self' and 'non-self' cells. When an organ from an unrelated donor is transplanted,

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Cell-mediated immunity

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(B) The body's immune system is capable of differentiating between 'self' and 'non-self' cells. When an organ from an unrelated donor is transplanted,the recipient's immune system recognizes the foreign antigens on the donor tissue. Cell-mediated immunity,primarily involving $T$-lymphocytes,plays the lead role in graft rejection. These $T$-cells identify the foreign cells and initiate an immune response to destroy the transplanted tissue.

Column $I$ (Type of Immunity)	Column $II$ (Example)
$i$. Natural acquired active	$a$. $BCG$ Vaccine
$ii$. Artificial acquired active	$b$. Immunity against measles
$iii$. Natural acquired passive	$c$. Colostrum
$iv$. Artificial acquired passive	$d$. Injections against rabies

Column-$I$	Column-$II$
$(a)$ Physical barrier	$(1)$ Skin
$(b)$ Physiological barrier	$(2)$ Interferon protein
$(c)$ Cellular barrier	$(3)$ Leucocytes
$(d)$ Cytokine barrier	$(4)$ Saliva in the mouth

After an organ transplant from an unrelated donor,which of the following plays the lead role in graft rejection?

Similar Questions

Which of the following is responsible for cell-mediated immunity?

The 'first line of defence' is known as:

Why is an antibody molecule represented as $H_2L_2$?

Match the columns:

Column-$I$ Column-$II$

$(a)$ Physical barrier $(1)$ Skin

$(b)$ Physiological barrier $(2)$ Interferon protein

$(c)$ Cellular barrier $(3)$ Leucocytes

$(d)$ Cytokine barrier $(4)$ Saliva in the mouth

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