Assertion: Phenylketonuria is a recessive her | vedclass

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(A) Phenylketonuria $(PKU)$ is an autosomal recessive genetic disorder.It is caused by the deficiency of the enzyme phenylalanine hydroxylase,which is

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If both Assertion and Reason are correct and the Reason is a correct explanation of the Assertion.

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(A) Phenylketonuria $(PKU)$ is an autosomal recessive genetic disorder.It is caused by the deficiency of the enzyme phenylalanine hydroxylase,which is responsible for converting the amino acid phenylalanine into tyrosine.Due to the lack of this enzyme,phenylalanine accumulates in the body and is converted into phenylpyruvic acid and other derivatives.These derivatives are excreted in the urine,hence the name Phenylketonuria. Therefore,both the Assertion and the Reason are correct,and the Reason explains why the condition is named as such and why the substance appears in the urine.

Assertion: Phenylketonuria is a recessive hereditary disease caused by the body's failure to oxidize the amino acid phenylalanine to tyrosine due to a defective enzyme.
Reason: It results in the presence of phenylalanine acid in urine.

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Assertion: Phenylketonuria is a recessive hereditary disease caused by the body's failure to oxidize the amino acid phenylalanine to tyrosine due to a defective enzyme.Reason: It results in the presence of phenylalanine acid in urine.