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(B) Down's syndrome is a chromosomal disorder caused by the presence of an additional copy of chromosome number $21$ (trisomy of $21$).Key clinical fe

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Down's syndrome

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(B) Down's syndrome is a chromosomal disorder caused by the presence of an additional copy of chromosome number $21$ (trisomy of $21$).Key clinical features of Down's syndrome include:$a.$ Broad palm with a characteristic single palm crease (simian crease).$b.$ Short stature with a small,round head.$c.$ Furrowed tongue and partially open mouth.$d.$ Physical,psychomotor,and mental development is retarded.

Broad palm with single palm crease is visible in a person suffering from-

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