Determine the correct configuration of the fo | vedclass

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(B) To determine the configuration,we assign priorities to the groups attached to each chiral center according to the Cahn-Ingold-Prelog $(CIP)$ rules

Vedclass · Accepted Answer

$2S, 3R$

Vedclass · Answer

(B) To determine the configuration,we assign priorities to the groups attached to each chiral center according to the Cahn-Ingold-Prelog $(CIP)$ rules.For the chiral center at $C-2$:$1$. $-Cl$ (priority $1$)$2$. $-CH(Cl)CH_3$ (priority $2$)$3$. $-CH_3$ (priority $3$)$4$. $-H$ (priority $4$)The sequence $1$ $\rightarrow 2$ $\rightarrow 3$ is clockwise,but since the lowest priority group $(-H)$ is on a horizontal bond,the configuration is inverted to $S$.For the chiral center at $C-3$:$1$. $-Cl$ (priority $1$)$2$. $-CH(Cl)CH_3$ (priority $2$)$3$. $-CH_3$ (priority $3$)$4$. $-H$ (priority $4$)The sequence $1$ $\rightarrow 2$ $\rightarrow 3$ is counter-clockwise,and since the lowest priority group $(-H)$ is on a horizontal bond,the configuration is inverted to $R$.Thus,the configuration is $2S, 3R$.

Determine the correct configuration of the following molecule:

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