Diuresis is a specific pathological condition which leads to

Kidney stones are produced due to deposition of uric acid and

$A -$ Malfunctioning of kidneys can lead to accumulation of urea in blood,a condition called uremia.
$R -$ Blood drained from a convenient artery is pumped into a dialyzing unit after adding an anticoagulant like heparin.

$A$ person suffering from diabetes insipidus will pass what amount of urine per day?

Choose the correct statements.
$I.$ Kidney transplantation is the terminal mode of treating kidney dysfunction.
$II.$ Close relatives are often used as kidney donors to minimise risk of rejection.
$III.$ Cyclosporin-$A$ is used as an immunosuppressive drug in kidney transplant patients.
$IV.$ Heparin and anti-heparin are used in haemodialysis.
Choose the correct option.

Which one of the following is likely to accumulate in a dangerous proportion in the blood of a person whose kidney is not working properly?