Gene mutation is caused by

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(C) Gene mutations are sudden,stable changes in the structure of a gene or cistron. These mutations occur due to alterations in the type or sequence o

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Change in the sequence of nitrogenous base

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(C) Gene mutations are sudden,stable changes in the structure of a gene or cistron. These mutations occur due to alterations in the type or sequence of nucleotides within the $DNA$ molecule. Since nitrogenous bases are the primary components of nucleotides,any change in their sequence directly alters the genetic code,leading to a gene mutation.

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