Give an account of Glycolysis. Where does it occur? What are the end products? Trace the fate of these products in both aerobic and anaerobic respiration.

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(N/A) Definition: Glycolysis is the process of partial oxidation of glucose into two molecules of pyruvic acid.
Origin: The term glycolysis originates from the Greek words 'glycos' (sugar) and 'lysis' (splitting). The scheme was proposed by Gustav Embden,Otto Meyerhof,and $J$. Parnas,hence it is known as the $EMP$ pathway.
Location: Glycolysis occurs in the cytoplasm of the cell.
Process: In plants,glucose is derived from sucrose (end product of photosynthesis) or storage carbohydrates. Glucose and fructose are phosphorylated to form glucose-$6$-phosphate by the enzyme hexokinase. This is then isomerized to fructose-$6$-phosphate,which is further converted to fructose-$1,6$-bisphosphate using $ATP$. Fructose-$1,6$-bisphosphate splits into dihydroxyacetone phosphate $(DHAP)$ and $3$-phosphoglyceraldehyde $(PGAL)$. $PGAL$ is oxidized to $1,3$-bisphosphoglycerate,producing $NADH + H^+$. Subsequent steps involve the production of $ATP$ through substrate-level phosphorylation,ultimately yielding two molecules of pyruvic acid $(3C)$.
End Products: The primary end product is pyruvic acid. Other products include $2$ molecules of $ATP$ (net gain) and $2$ molecules of $NADH + H^+$.
Fate of Pyruvic Acid:
$1$. Lactic Acid Fermentation: Occurs in some bacteria and muscle cells under anaerobic conditions,converting pyruvate to lactic acid.
$2$. Alcoholic Fermentation: Occurs in yeast under anaerobic conditions,converting pyruvate to ethanol and $CO_2$.
$3$. Aerobic Respiration: In the presence of oxygen,pyruvic acid enters the mitochondria,undergoes oxidative decarboxylation to form Acetyl-$CoA$,and enters the Krebs cycle for complete oxidation into $CO_2$ and $H_2O$.

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Similar Questions

What is the other name of glycolysis?

Assertion : Glycolysis occurs in the cytoplasm.
Reason : Enzymes for glycolysis are found in the cytoplasm. It is common in aerobic and anaerobic respiration.

How many types of enzymes are required for the completion of the process of glycolysis?

In which of the following steps of glycolysis is $ATP$ utilized?

In both aerobic and anaerobic respiration,which product is formed in common?

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