In Huntington's disease,the unaffected person | vedclass

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Question

(B) Huntington's disease is an autosomal dominant disorder. In an autosomal dominant pedigree,an affected individual must have at least one affected p

Vedclass · Accepted Answer

either person $6$ or $7$ should have the disease,if individual $11$ shows the disease.

Vedclass · Answer

(B) Huntington's disease is an autosomal dominant disorder. In an autosomal dominant pedigree,an affected individual must have at least one affected parent.In the given pedigree,individual $11$ is affected (represented by a filled circle). Since the disease is autosomal dominant,at least one of her parents ($6$ or $7$) must also be affected (represented by a filled symbol).However,in the pedigree,both individuals $6$ and $7$ are unaffected (represented by empty symbols). Therefore,this pedigree is erroneous because it violates the rule of autosomal dominant inheritance.

In Huntington's disease,the unaffected persons are homozygous for normal allele $h$. The following pedigree is erroneous because:

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