In sickle cell anaemia,the death is caused wh | vedclass

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(C) Sickle cell anaemia is an autosomal recessive genetic disorder caused by a mutation in the $Hb^S$ gene.In the heterozygous condition $(Hb^A Hb^S)$

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Homozygous recessive condition

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(C) Sickle cell anaemia is an autosomal recessive genetic disorder caused by a mutation in the $Hb^S$ gene.In the heterozygous condition $(Hb^A Hb^S)$,the individual is a carrier and exhibits the sickle cell trait,which provides some resistance to malaria.In the homozygous recessive condition $(Hb^S Hb^S)$,the individual suffers from severe sickle cell anaemia.This condition leads to the production of abnormal haemoglobin,causing red blood cells to become sickle-shaped,which results in severe anaemia and often leads to premature death due to organ failure and complications. Thus,the lethal effect is observed in the homozygous recessive state.

In sickle cell anaemia,the death is caused when the lethal genes are present in

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