List two causes of depletion of the ozone layer. Mention any two harmful effects of the depletion of this layer.

(N/A) Two causes of the depletion of the ozone layer are:
$(i)$ Use of $CFCs$ (Chlorofluorocarbons) in refrigeration.
$(ii)$ Use of $CFCs$ in fire extinguishers and aerosol sprayers.
The harmful effects of the depletion of the ozone layer are:
$(i)$ Due to the depletion of the ozone layer,$UV$ radiations reach the Earth. These $UV$ radiations cause skin cancer,damage to eyes,and harm the immune system.
$(ii)$ This depletion of the ozone layer may also lead to variations in global rainfall,ecological disturbances,and a decrease in global food supplies.