Match the columns:

Column-$I$	Column-$II$
$(1)$ Diabetes	$(a)$ $ADA$
$(2)$ Enzyme replacement therapy	$(b)$ Alpha-lactalbumin
$(3)$ Emphysema	$(c)$ Insulin
$(4)$ Rosie cow	$(d)$ $\alpha-1$-Antitrypsin
	$(e)$ Typhoid

In $1990$,which therapy was given to a four-year-old girl suffering from adenosine deaminase $(ADA)$ deficiency?

Consider the following statements about insulin.
$I.$ Human insulin is made up of $51$ amino acids arranged in two polypeptide chains.
$II.$ The two polypeptide chains are interconnected by two disulphide bridges.
$III.$ In mammals,including humans,insulin is synthesised as a pro-hormone,which contains an extra stretch called the $C$-peptide.
$IV.$ $C$-peptide is not present in the mature insulin.
Which of the statements given above are correct?

In modern times,animal cell culture technology is primarily used for the production of which of the following?

Which kind of therapy was given in $1990$ to a four-year-old girl with adenosine deaminase $(ADA)$ deficiency?

Consider the following statements about therapeutic drugs:
$I$. The recombinant $DNA$ technology is used for the production of therapeutic drugs which are safe and effective.
$II$. It avoids unwanted immunological responses,commonly observed with similar products isolated from non-human sources.
$III$. About $30$ recombinant therapeutics have been approved for human use in the world,including India.
Which of the statements given above are correct?