Match the following:

Column-$I$	Column-$II$
$(1)$ Study of disease	$(p)$ Transgenic mice
$(2)$ Biological products	$(q)$ Testing toxicity of drug
$(3)$ Vaccine safety	$(r)$ Rheumatoid arthritis
$(4)$ Chemical safety	$(s)$ $\alpha-1$ Antitrypsin

• A
  $(1-p), (2-q), (3-r), (4-s)$
• B
  $(1-r), (2-s), (3-q), (4-p)$
• C
  $(1-r), (2-s), (3-p), (4-q)$
• D
  $(1-p), (2-r), (3-q), (4-s)$