Nicotine is

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(D) Tobacco contains a large number of chemical substances,including nicotine,which is an alkaloid.Nicotine acts as a stimulant by binding to nicotini

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Both $(a)$ and $(c)$

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(D) Tobacco contains a large number of chemical substances,including nicotine,which is an alkaloid.Nicotine acts as a stimulant by binding to nicotinic acetylcholine receptors.It stimulates the adrenal glands to release adrenaline and noradrenaline into the blood circulation.Both of these hormones increase blood pressure and heart rate.

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