Pests resistant to insecticides have:

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(D) Pests develop resistance to insecticides through various physiological and biochemical mechanisms. $1$. Less permeable cuticles: This reduces the

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(D) Pests develop resistance to insecticides through various physiological and biochemical mechanisms. $1$. Less permeable cuticles: This reduces the rate of absorption of the insecticide into the pest's body. $2$. Faster storage of toxin in fat: This sequesters the toxin away from the target site,preventing immediate harm. $3$. Enzymes for metabolising toxin: Many resistant pests possess specific enzymes (like cytochrome $P450$ monooxygenases) that break down the insecticide into non-toxic metabolites. Since all these mechanisms contribute to insecticide resistance,the correct answer is $D$.

Column-$I$	Column-$II$
$(A)$ Amoebiasis	$(i)$ Treponema pallidum
$(B)$ Diphtheria	$(ii)$ Use only sterilized food and water
$(C)$ Cholera	$(iii)$ $DPT$ Vaccine
$(D)$ Syphilis	$(iv)$ Use oral rehydration therapy

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