Sickle cell anaemia is more common in certain regions due to evolutionary adaptations against malaria. The molecular basis of this disease is:

  • A
    Change in $\beta$-chain of haemoglobin
  • B
    More population of house flies
  • C
    Change in $\alpha$-chain of haemoglobin
  • D
    Change in $\gamma$-chain of haemoglobin

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Similar Questions

Identify the genetic disorders based on the following characteristics:
$(i)$ Presence of sickle-shaped $RBC$.
$(ii)$ Blood does not clot,leading to non-stop bleeding.
$(iii)$ The heterozygous female transmits the disease to sons.
$(iv)$ Both heterozygous parents transmit the disease to offspring.

Thalassemia and Sickle cell anaemia are caused by problems in globin molecule synthesis. Select the correct statement.

Which type of abnormality is seen in the given pedigree chart?

Color blindness is more common in males because it is a:

$A$ normal woman,whose father was colourblind,marries a normal man. What kinds of children can be expected and in what proportion?

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