Sickle-cell anemia has not been eliminated fr | vedclass

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(C) Sickle-cell anemia is caused by a mutation in the $Hb^S$ gene. Individuals who are heterozygous $(Hb^A Hb^S)$ for the sickle-cell trait possess a

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It provides immunity against malaria.

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(C) Sickle-cell anemia is caused by a mutation in the $Hb^S$ gene. Individuals who are heterozygous $(Hb^A Hb^S)$ for the sickle-cell trait possess a survival advantage in regions where malaria is endemic. The presence of some sickled red blood cells inhibits the growth and reproduction of the malaria parasite $(Plasmodium)$. This phenomenon is known as balanced polymorphism or heterozygote advantage,which maintains the $Hb^S$ allele in the population despite the disease being lethal in the homozygous recessive $(Hb^S Hb^S)$ condition.

Sickle-cell anemia has not been eliminated from the African population because,........

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