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(C) $MSH$ (Melanocyte Stimulating Hormone) is responsible for the darkening of the skin by stimulating melanin production. Conversely,Melatonin is the

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Melatonin

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(C) $MSH$ (Melanocyte Stimulating Hormone) is responsible for the darkening of the skin by stimulating melanin production. Conversely,Melatonin is the hormone secreted by the pineal gland that acts as an antagonist to $MSH$ in many vertebrates,leading to the lightening of the skin. The secretion of Melatonin is regulated by light intensity; it increases in dim light and decreases in bright light.

Suggest a suitable word for the fourth place: Darkening of skin : $MSH$ :: Lightening of skin : .......

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