The correct structure of histidine in a stron | vedclass

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(A) Histidine is an amino acid with three ionizable groups: the $\alpha$-amino group,the $\alpha$-carboxyl group,and the imidazole side chain. In a st

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(A) Histidine is an amino acid with three ionizable groups: the $\alpha$-amino group,the $\alpha$-carboxyl group,and the imidazole side chain. In a strongly acidic solution $(pH = 2)$,the concentration of $H^{+}$ ions is very high. At this $pH$,all basic groups will be protonated: $1$. The carboxyl group exists as $-COOH$ (since $pH $2$. The $\alpha$-amino group exists as $-NH_3^+$. $3$. The imidazole side chain also gets protonated to exist as an imidazolium ion $(-NH^+)$. Therefore,the structure will have a net charge of $+2$. This corresponds to the structure shown in option $A$.

The correct structure of histidine in a strongly acidic solution $(pH = 2)$ is

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