The following reaction represents:alpha-ketog | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

$(A)$ The organic acid, $\alpha$-ketoglutaric acid, plays a key role in the synthesis of amino acids.In this process, ammonia $(NH_{4}^{+})$ formed by

Vedclass · Accepted Answer

Reductive amination

Vedclass · Answer

$(A)$ The organic acid, $\alpha$-ketoglutaric acid, plays a key role in the synthesis of amino acids.In this process, ammonia $(NH_{4}^{+})$ formed by nitrogen assimilation reacts with $\alpha$-ketoglutaric acid to form an amino acid, i.e., glutamic acid (glutamate).This reaction is catalyzed by the enzyme glutamate dehydrogenase.Since the reaction involves the addition of an amino group and the reduction of the substrate using $NADPH$, it is known as reductive amination.

The following reaction represents:
$\alpha$-ketoglutaric acid $+ NH_{4}^{+} + NADPH \xrightarrow{\text{Glutamate dehydrogenase}} \text{Glutamate} + H_{2}O + NADP$

Similar Questions

Identify the chemical reaction and the enzyme involved in the given process.

Which of the following is an example of a nutrient in its reduced form?

Amino acids are mostly synthesised from

Which mineral element plays a crucial role in nitrogen metabolism?

Give differences: Reductive Amination and Transamination.

Vedclass Test Series

Exam Paper Generator

Online Exam Module

The following reaction represents:$\alpha$-ketoglutaric acid $+ NH_{4}^{+} + NADPH \xrightarrow{\text{Glutamate dehydrogenase}} \text{Glutamate} + H_{2}O + NADP$