The major product obtained in the following r | vedclass

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(D) The reactant is $2$-amino-$1$-phenylpropan-$1$-ol. It contains both an amino group $(-NH_2)$ and a hydroxyl group $(-OH)$.When treated with acetic

Vedclass · Accepted Answer

$A$ structure showing an acetamide group at the amino position with the hydroxyl group intact.

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(D) The reactant is $2$-amino-$1$-phenylpropan-$1$-ol. It contains both an amino group $(-NH_2)$ and a hydroxyl group $(-OH)$.When treated with acetic anhydride $((CH_3CO)_2O)$ in the presence of pyridine at room temperature,acetylation occurs.Since the nucleophilicity of the amino group $(-NH_2)$ is significantly higher than that of the hydroxyl group $(-OH)$,the amino group undergoes acetylation preferentially to form an amide.Therefore,the major product is the $N$-acetylated derivative,where the $-NH_2$ group is converted to $-NHCOCH_3$ while the $-OH$ group remains unchanged.

The major product obtained in the following reaction is:

Similar Questions

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