The most important example of point mutation | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(D) Sickle-cell anaemia is a classic example of a point mutation.It is caused by a single base pair substitution in the gene coding for the $\beta$-gl

Vedclass · Accepted Answer

Sickle-cell anaemia

Vedclass · Answer

(D) Sickle-cell anaemia is a classic example of a point mutation.It is caused by a single base pair substitution in the gene coding for the $\beta$-globin chain of hemoglobin.Specifically,the codon $GAG$ is replaced by $GUG$ at the sixth position of the $\beta$-globin chain.This results in the substitution of the amino acid glutamic acid with valine,which leads to the formation of abnormal hemoglobin $(HbS)$ and causes the red blood cells to become sickle-shaped under low oxygen tension.

The most important example of point mutation is found in a disease called

Similar Questions

On which plant did Hugo de Vries work?

Point mutation arises due to change in

Mutations are caused due to

Which of the following mutagens causes frame-shift mutations?

What does a point mutation involve?

Vedclass Test Series

Exam Paper Generator

Online Exam Module