What is caused by prolonged disturbance in the secretion of hormones from the thyroid gland?

What is the effect of $Thyroxine$ on the metabolic rate?

$A$ health disorder that results from the deficiency of thyroxine in adults and is characterised by $(i)$ a low metabolic rate,$(ii)$ an increase in body weight,and $(iii)$ a tendency to retain water in tissues is:

Graves' disease is caused due to

$A$ pregnant woman delivers a child who suffers from stunted growth,mental retardation,low intelligence quotient $(IQ)$,and abnormal skin. This condition is likely due to:

Which substance should be added to water to accelerate the process of metamorphosis in tadpoles?