Which disease serves as the most classic exam | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(C) frameshift mutation occurs due to the insertion or deletion of nucleotides in a $DNA$ sequence,which shifts the reading frame of the genetic code.

Vedclass · Accepted Answer

Lesch-Nyhan syndrome

Vedclass · Answer

(C) frameshift mutation occurs due to the insertion or deletion of nucleotides in a $DNA$ sequence,which shifts the reading frame of the genetic code. $Lesch-Nyhan$ syndrome is a classic example of a genetic disorder often associated with various types of mutations,including frameshift mutations,which lead to the deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase $(HGPRT)$. Sickle cell anemia is typically caused by a point mutation (substitution),while thalassemia is often caused by mutations affecting globin chain synthesis,which can include frameshift mutations,but $Lesch-Nyhan$ syndrome is frequently cited in textbooks as a specific example related to such genetic alterations.

Which disease serves as the most classic example of a frameshift mutation?

Similar Questions

What is the effect of a change in a single base pair of $DNA$?

Sometimes cattle or even human beings give birth to their young ones that have extremely different sets of organs,such as limbs or the position of eyes. Comment.

Which one of the following mutations partially or fully reverses the harmful effects of a previous mutation?

What causes gene mutation?

Which of the following pairs is correct?

Vedclass Test Series

Exam Paper Generator

Online Exam Module