Which of the following pairs is mismatched?

Which of the following is not used for the disinfection of drinking water?

Microbes are used in:
$1.$ Primary treatment of sewage
$2.$ Secondary treatment of sewage
$3.$ Anaerobic sludge digester
$4.$ Production of bioactive molecules

The deadly disease for which antibiotics were discovered is/are ......... .

Which of the following pairs is not correctly matched?

Consider the following statements:
$I.$ Yeast used in making bread and beverages is a prokaryotic fungus.
$II.$ Streptokinase is produced by $Streptococcus$ and modified by genetic engineering is used as a clot buster.
$III.$ Lipases are added in detergent for removing only stains from laundry.
$IV.$ Pectinases are used in clearing fruit juices.
Which of the statements given above are correct?