Which sentence is true for the disease Tetany?

$A$ condition in which the inguinal canal becomes loose in a middle-aged person and a part of the intestine is pushed into the scrotum is called..........

Sprain is caused due to excessive pulling of

Assertion: Inflammation of a skeletal joint may immobilize the movements of the joint.
Reason: Uric acid crystals in the joint cavity and ossification of articular cartilage lead to this.

Given below are two statements: one is labelled as Assertion $(A)$ and the other is labelled as Reason $(R)$.
Assertion $(A)$:
Osteoporosis is characterised by decreased bone mass and increased chances of fractures.
Reason $(R)$:
Common cause of osteoporosis is increased levels of estrogen.
In the light of the above statements,choose the most appropriate answer from the options given below:

Osteoporosis,an age-related disease of the skeletal system,may occur due to: