Who first realized the use of yeast in fermentation?

Which of the following can be the use of micro-organisms?

$S$ (Assertion): Alexander Fleming established the full potential of penicillin as an effective antibiotic.
$R$ (Reason): Alexander Fleming discovered penicillin.

Who was the first discoverer of antibiotics?

$A$: Microbes have been used for the welfare of humanity.
$R$: The fields of biotechnology and genetic engineering have developed.

Identify the correct statements with respect to antibiotics:
$(i)$ Fleming,Chain,and Florey were awarded the Nobel Prize in $1945$.
$(ii)$ Antibiotics have greatly improved our capacity to treat deadly diseases.
$(iii)$ Penicillin was used to treat American soldiers wounded in World War $I$.