In what form does the Bt toxin get converted | vedclass

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Question

(B) The $Bt$ toxin produced by the bacterium $Bacillus$ $thuringiensis$ exists as an inactive protoxin in the form of crystalline inclusions within th

Vedclass · Accepted Answer

Active soluble protein

Vedclass · Answer

(B) The $Bt$ toxin produced by the bacterium $Bacillus$ $thuringiensis$ exists as an inactive protoxin in the form of crystalline inclusions within the bacterial cell.When an insect ingests this inactive protein,it reaches the midgut of the insect.The midgut of the insect provides an alkaline $pH$ environment.This alkaline $pH$ solubilizes the crystals,converting the inactive protoxin into its active,soluble toxic form.This active toxin then binds to the surface of midgut epithelial cells,creating pores that cause cell swelling and lysis,eventually leading to the death of the insect.

In what form does the $Bt$ toxin get converted in an alkaline $pH$ medium?

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