How is a permanent cure for ADA deficiency po | vedclass

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(C) The permanent cure for $ADA$ (Adenosine Deaminase) deficiency is gene therapy.In this method,lymphocytes from the blood of the patient are grown i

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Introducing $ADA$ producing genes into cells at early embryonic stages

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(C) The permanent cure for $ADA$ (Adenosine Deaminase) deficiency is gene therapy.In this method,lymphocytes from the blood of the patient are grown in a culture outside the body.$A$ functional $ADA$ $cDNA$ is then introduced into these lymphocytes using a retroviral vector.These genetically engineered cells are then returned to the patient.However,since these cells are not immortal,the patient requires periodic infusion of such genetically engineered lymphocytes.If the gene isolate from marrow cells producing $ADA$ is introduced into cells at early embryonic stages,it could be a permanent cure.

How is a permanent cure for $ADA$ deficiency possible?

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