Assertion : Persons suffering from haemophili | vedclass

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(C) Haemophilia is a group of hereditary genetic disorders that impair the body's ability to control blood clotting or coagulation.In its most common

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If the Assertion is correct but Reason is incorrect.

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(C) Haemophilia is a group of hereditary genetic disorders that impair the body's ability to control blood clotting or coagulation.In its most common form,Haemophilia $A$,the blood clotting factor $VIII$ is absent or deficient.In Haemophilia $B$,factor $IX$ is deficient.Factor $VIII$ acts as a cofactor for factor $IXa$,which in the presence of $Ca^{+2}$ and phospholipids,forms a complex that converts factor $X$ to its activated form,$Xa$.Defects in the gene encoding factor $VIII$ result in Haemophilia $A$,which is a recessive $X$-linked coagulation disorder.The Reason statement is incorrect because the concentration of platelets in haemophilia patients is typically normal; the disorder is caused by a deficiency in specific clotting factors,not a deficiency in platelet count or prothrombin production.

Assertion : Persons suffering from haemophilia fail to produce blood clotting factor $VIII$.
Reason : Prothrombin producing platelets in such persons are found in very low concentration.

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Assertion : Persons suffering from haemophilia fail to produce blood clotting factor $VIII$.Reason : Prothrombin producing platelets in such persons are found in very low concentration.