Base substitution caused by base analogs is k | vedclass

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(A) Base analogs are chemical compounds that are structurally similar to normal nitrogenous bases of $DNA$. Because of their structural similarity,the

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Transition

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(A) Base analogs are chemical compounds that are structurally similar to normal nitrogenous bases of $DNA$. Because of their structural similarity,they can be incorporated into the $DNA$ molecule during replication in place of the normal bases. For example,$5$-bromouracil ($5$-$BU$) acts as an analog of thymine and can pair with guanine instead of adenine. This leads to a point mutation where one purine is replaced by another purine or one pyrimidine is replaced by another pyrimidine. This specific type of base substitution is known as $Transition$.

Column $I$	Column $II$
$1$. Ligase	$a$. Peptide bond formation
$2$. Ribozyme	$b$. Hydrolysis of lactose
$3$. Permease	$c$. Joining of Okazaki fragments
$4$. $\beta$-galactosidase	$d$. Increases permeability

Column-$I$	Column-$II$
$(A)$ $DNA$ replication	$(p)$ $RNA$ polymerase
$(B)$ Translation	$(q)$ $DNA$ polymerase
$(C)$ Transcription	$(r)$ Reverse transcriptase
$(D)$ Reverse transcription	$(s)$ Aminoacyl synthetase

Base substitution caused by base analogs is known as:

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