| $DNA$ | $RNA$ |
| $(1)$ It is a double-stranded polynucleotide chain. | $(1)$ It is a single-stranded polynucleotide chain. |
| $(2)$ It contains $A, C, G,$ and $T$ nitrogenous bases. | $(2)$ It contains $A, C, G,$ and $U$ nitrogenous bases. |
| $(3)$ It is primarily present in the nucleus,chloroplasts,and mitochondria. | $(3)$ It is present in the nucleus and cytoplasm. |
| $(4)$ It stores and transmits genetic information across generations. | $(4)$ It regulates the expression of genetic information through protein synthesis. |
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