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(B) The production of insulin using recombinant $DNA$ technology was achieved by the American company Eli Lilly in $1983$.They synthesized two $DNA$ s

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Disulphide bond

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(B) The production of insulin using recombinant $DNA$ technology was achieved by the American company Eli Lilly in $1983$.They synthesized two $DNA$ sequences corresponding to the $A$ and $B$-chains of human insulin and introduced them into the plasmids of $Escherichia$ $coli$ ($E$. $coli$) to produce the respective chains.The $A$ and $B$ chains were produced separately,extracted from the bacterial cells,and then combined by creating disulphide bonds to form functional human insulin.

In $1983$,Eli Lilly,an American company,first prepared two $DNA$ sequences corresponding to $A$ and $B$-chains of human insulin and introduced them into the plasmids of $Escherichia$ $coli$ to produce insulin chains. Chains $A$ and $B$ were prepared separately,extracted,and combined by creating:

Similar Questions

Which one of the following is now being commercially produced by biotechnological procedures?

Which one of the following is the first genetically engineered medicine?

The disadvantage of using porcine insulin in diabetic patients is

Abnormal genes are replaced by normal genes through:

Assertion: $C$-peptide is not present in the mature insulin.
Reason: Insulin used for diabetes was earlier extracted from the pancreas of slaughtered cattle and pigs.

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