Mark the correct statement with respect to sickle-cell anaemia.

  • A
    Homozygous individuals for $Hb^{S}$ are apparently unaffected.
  • B
    Heterozygous individuals exhibit sickle-cell trait.
  • C
    Heterozygous individuals are affected as well as carriers.
  • D
    Homozygous individuals for $Hb^{A}$ show the diseased phenotype.

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