Match the columns :
Column-$I$Column-$II$
$(a)$ Statin$(1)$ To remove oily stains
$(b)$ Cyclosporin $A$$(2)$ To break blood clot
$(c)$ Streptokinase$(3)$ To decrease cholesterol in blood
$(d)$ Lipase$(4)$ Component to reduce blood immunity

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(A) The correct matches are as follows:
$(a)$ Statin is produced by the yeast $Monascus$ $purpureus$ and acts as a blood-cholesterol lowering agent $(a-3)$.
$(b)$ Cyclosporin $A$ is produced by the fungus $Trichoderma$ $polysporum$ and is used as an immunosuppressive agent in organ transplant patients $(b-4)$.
$(c)$ Streptokinase is produced by the bacterium $Streptococcus$ and is used as a 'clot buster' for removing clots from the blood vessels of patients who have undergone myocardial infarction $(c-2)$.
$(d)$ Lipase is used in detergent formulations and is helpful in removing oily stains from the laundry $(d-1)$.
Therefore, the correct sequence is $(a-3, b-4, c-2, d-1)$.

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MicrobeProductApplication
$(a)$ StreptococcusStreptokinaseRemoval of clot from blood vessel
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