(B) $Sickle$ $cell$ $anaemia$ is caused due to a point mutation in which glutamic acid is replaced by valine at the $6th$ position of the $\beta$-glob

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Thalassemia is due to less synthesis of globin molecules.

(B) $Sickle$ $cell$ $anaemia$ is caused due to a point mutation in which glutamic acid is replaced by valine at the $6th$ position of the $\beta$-globin chain. Thus,it is a qualitative defect in the functioning of globin molecules.$Thalassemia$ is caused due to either mutation or deletion,which ultimately results in a reduced rate of synthesis of one of the globin chains that make up haemoglobin. Hence,it is a quantitative defect in the functioning of globin molecules.

Class 12 Biology Principles of Inheritance and Variation Pedigree Analysis and Mendelian disorders

Medium

Thalassemia and sickle cell anaemia are caused due to a problem in globin molecule synthesis. Select the correct statement.

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A
Both are due to a quantitative defect in globin chain synthesis.
B
Thalassemia is due to less synthesis of globin molecules.
C
Sickle cell anaemia is due to a quantitative problem of globin molecules.
D
Both are due to a qualitative defect in globin chain synthesis.

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Chapter

Principles of Inheritance and Variation

Subtopic

Pedigree Analysis and Mendelian disorders

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Select the correct options for the given statements:
Statements:
$X$: Formation of Haemoglobin is controlled by two closely linked genes $HBA1$ and $HBA2$ on chromosome $16$ of each parent.
$Y$: $\beta$-Thalassemia is controlled by a single gene $HBB$ on chromosome $21$ of each parent.

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Which one of the following disorders is caused by the substitution of Glutamic acid (Glu) by Valine (Val) at the sixth position of the beta globin chain of the haemoglobin molecule?

MediumNEET 2026

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Genetic counsellors can identify heterozygous individuals by

Medium

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If all the sons are haemophilic and all the daughters are normal when a haemophilic father mates with a normal mother,this character is:

DifficultAIPMT 1996

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Which of the following genotypes causes sickle cell anemia?

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Thalassemia and sickle cell anaemia are caused due to a problem in globin molecule synthesis. Select the correct statement.

Similar Questions

Select the correct options for the given statements:Statements:$X$: Formation of Haemoglobin is controlled by two closely linked genes $HBA1$ and $HBA2$ on chromosome $16$ of each parent.$Y$: $\beta$-Thalassemia is controlled by a single gene $HBB$ on chromosome $21$ of each parent.

Which one of the following disorders is caused by the substitution of Glutamic acid (Glu) by Valine (Val) at the sixth position of the beta globin chain of the haemoglobin molecule?

Genetic counsellors can identify heterozygous individuals by

If all the sons are haemophilic and all the daughters are normal when a haemophilic father mates with a normal mother,this character is:

Which of the following genotypes causes sickle cell anemia?

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Select the correct options for the given statements:
Statements:
$X$: Formation of Haemoglobin is controlled by two closely linked genes $HBA1$ and $HBA2$ on chromosome $16$ of each parent.
$Y$: $\beta$-Thalassemia is controlled by a single gene $HBB$ on chromosome $21$ of each parent.